Power calculation for cross‐sectional stepped wedge cluster randomized trials with variable cluster sizes
نویسندگان
چکیده
منابع مشابه
Design and analysis of stepped wedge cluster randomized trials.
Cluster randomized trials (CRT) are often used to evaluate therapies or interventions in situations where individual randomization is not possible or not desirable for logistic, financial or ethical reasons. While a significant and rapidly growing body of literature exists on CRTs utilizing a "parallel" design (i.e. I clusters randomized to each treatment), only a few examples of CRTs using cro...
متن کاملUnequal cluster sizes in stepped-wedge cluster randomised trials: a systematic review
OBJECTIVES To investigate the extent to which cluster sizes vary in stepped-wedge cluster randomised trials (SW-CRT) and whether any variability is accounted for during the sample size calculation and analysis of these trials. SETTING Any, not limited to healthcare settings. PARTICIPANTS Any taking part in an SW-CRT published up to March 2016. PRIMARY AND SECONDARY OUTCOME MEASURES The pr...
متن کاملGroup sequential designs for stepped-wedge cluster randomised trials
BACKGROUND/AIMS The stepped-wedge cluster randomised trial design has received substantial attention in recent years. Although various extensions to the original design have been proposed, no guidance is available on the design of stepped-wedge cluster randomised trials with interim analyses. In an individually randomised trial setting, group sequential methods can provide notable efficiency ga...
متن کاملStepped-wedge cluster randomised trials: where, when and why?
The stepped wedge (SW) cluster randomised trial (CRT) design is being utilised at increasing pace. However, little is known about the standard of reporting of such trials, or how useful the design has proven to be in hindsight. Moreover, much debate exists around when the design should be preferred to the more classical parallel group (PG) CRT. Here, we address these issues by first conducting ...
متن کاملThe use of permutation tests for the analysis of parallel and stepped-wedge cluster-randomized trials.
We investigate the use of permutation tests for the analysis of parallel and stepped-wedge cluster-randomized trials. Permutation tests for parallel designs with exponential family endpoints have been extensively studied. The optimal permutation tests developed for exponential family alternatives require information on intraclass correlation, a quantity not yet defined for time-to-event endpoin...
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ژورنال
عنوان ژورنال: Biometrics
سال: 2019
ISSN: 0006-341X,1541-0420
DOI: 10.1111/biom.13164